Cruella de Vil Eva Hooten/Hannah Holbrook Roger Dominic Giardino/Brandon Rodriguez Anita Cali Saturn/Alex Lichtl Horace Clyde Canizares/Max Mealor Jasper Shane Oldham/Hunter Saturn Narrator 1 Natalie Castaldo/Morgan NelsonNarrator 2 Tess Sody/Anastasia Solenz
Narrator 3 Justine Ortega/Christian HicksNarrator 4 Jazmine Windley/Sara Dodomead Pongo William Smith/Andrew Krabbs Perdita Yanaiz Morales/Madison Dorman Sgt. Tibbs Andrea Kressler/Jack Campeau Patch Brittany Mira/Lauren KiltenickLucky Ophelia Baloy/Zoe Jackson Pepper Camden Switzer/Nena Guzman Spot Tristan Blackwell/Anthony CabreraDot Talia Santago/Taryn AdamsPenny Tabitha Alonzo Boxer 1 Meghan Barter Boxer 2 Kayla Galvin/Kaile Miller Scottie 1 Elizabeth Darce/Mallory Cerkleski Scottie 2 Katia Galvan/Caya CooperPoodle 1 Celestine Bunty/Rachel Wilcox Poodle 2 Molly Stanich/Eleana Castro Chihuahua 1 Gabriella Sonzongni/Elizabeth Carreaga Chihuahua 2 Savannah Camposano/Jason Hoeffer Nanny Chanice Dos Santos Jenna AlbanoPolice Officerand Dog Catcher Anthony Owen/Austin Rodriguez